5Z8S

Human Mitochondrial ferritin mutant - C102A/C130A/E27C/E61C/E62C

5Z8S の概要

• エントリーDOI: 10.2210/pdb5z8s/pdb
• 分子名称: Ferritin, mitochondrial, GOLD ION (3 entities in total)
• 機能のキーワード: mitochondrail ferritin, gold, cysteine, metal binding protein, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21200.21

構造登録者

Zang, J.,Zheng, B.,Zhao, G. (登録日: 2018-02-01, 公開日: 2019-02-06, 最終更新日: 2024-03-27)

主引用文献

Zang, J.,Zheng, B.,Zhang, X.,Arosio, P.,Zhao, G.
Design and site-directed compartmentalization of gold nanoclusters within the intrasubunit interfaces of ferritin nanocage.
J Nanobiotechnology, 17:79-79, 2019

PubMed Abstract: Protein nanocages have emerged as popular nanocarriers for either drug delivery or biotemplates for the preparation of nanomaterials. However, only three interfaces, namely exterior surface, intersubunit and inner cavity, have been used as reaction sites for the above purposes with all known protein nanocages. On the other hand, how to control the site of Au NCs formed within a targeted protein template while maintaining the functionality of protein itself remains challenging.

PubMed: 31277668
DOI: 10.1186/s12951-019-0512-0

実験手法

X-RAY DIFFRACTION (1.973 Å)