5Z75

Artificial L-threonine 3-dehydrogenase designed by ancestral sequence reconstruction.

5Z75 の概要

• エントリーDOI: 10.2210/pdb5z75/pdb
• 分子名称: Artificial L-threonine 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: ancestral sequence reconstruction, l-threonine 3-dehydrogenase, oxidoreductase
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 151937.91

構造登録者

Nakano, S.,Motoyama, T.,Miyashita, Y.,Ishizuka, Y.,Matsuo, N.,Tokiwa, H.,Shinoda, S.,Asano, Y.,Ito, S. (登録日: 2018-01-27, 公開日: 2018-08-22, 最終更新日: 2023-11-22)

• 主引用文献: Nakano, S.,Motoyama, T.,Miyashita, Y.,Ishizuka, Y.,Matsuo, N.,Tokiwa, H.,Shinoda, S.,Asano, Y.,Ito, S.; Benchmark Analysis of Native and Artificial NAD+-Dependent Enzymes Generated by a Sequence-Based Design Method with or without Phylogenetic Data.; Biochemistry, 57:3722-3732, 2018; PubMed: 29787243; DOI: 10.1021/acs.biochem.8b00339

実験手法

X-RAY DIFFRACTION (2.1 Å)