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5Z19

The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine

Summary for 5Z19
Entry DOI10.2210/pdb5z19/pdb
DescriptorBeta-glucuronidase, (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid (3 entities in total)
Functional Keywordsbeta-glucuronidase, gh2, hydrolase
Biological source[Ruminococcus] gnavus
Total number of polymer chains6
Total formula weight437579.77
Authors
Dashnyam, P.,Lin, H.Y.,Lin, C.H. (deposition date: 2017-12-25, release date: 2018-12-12, Last modification date: 2024-03-27)
Primary citationDashnyam, P.,Mudududdla, R.,Hsieh, T.J.,Lin, T.C.,Lin, H.Y.,Chen, P.Y.,Hsu, C.Y.,Lin, C.H.
Dissection of the substrate preference and structure of gut microbial beta-glucuronidases identifies the major bacteria causing xenobiotic toxicity
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.503 Å)
Structure validation

217705

數據於2024-03-27公開中

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