5YY4
Crystal structure of the scFv antibody 4B08 with sulfated epitope peptide
Summary for 5YY4
Entry DOI | 10.2210/pdb5yy4/pdb |
Descriptor | scFv 4B08, C-C chemokine receptor type 5, SULFATE ION, ... (5 entities in total) |
Functional Keywords | antibody, biomolecular recognition, md simulations, thermodynamics, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 2 |
Total formula weight | 28394.64 |
Authors | Caaveiro, J.M.M.,Miyanabe, K.,Tsumoto, K. (deposition date: 2017-12-07, release date: 2018-07-18, Last modification date: 2023-11-22) |
Primary citation | Miyanabe, K.,Yamashita, T.,Abe, Y.,Akiba, H.,Takamatsu, Y.,Nakakido, M.,Hamakubo, T.,Ueda, T.,Caaveiro, J.M.M.,Tsumoto, K. Tyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody Biochemistry, 57:4177-4185, 2018 Cited by PubMed: 29936828DOI: 10.1021/acs.biochem.8b00592 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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