5YWF

Crystal structure of 2H4 Fab

Summary for 5YWF

• Entry DOI: 10.2210/pdb5ywf/pdb
• Descriptor: 2H4 light chain, 2H4 heavy chain (3 entities in total)
• Functional Keywords: flaviviruses, viral encephalitis, neutralizing monoclonal antibodies, structural analysis, viral entry, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 4
• Total formula weight: 94355.22

Authors

Qiu, X.,Lei, Y.,Yang, P.,Gao, Q.,Wang, N.,Cao, L.,Wang, X.,Xu, Z.K.,Rao, Z. (deposition date: 2017-11-29, release date: 2018-03-21)

• Primary citation: Qiu, X.,Lei, Y.,Yang, P.,Gao, Q.,Wang, N.,Cao, L.,Yuan, S.,Huang, X.,Deng, Y.,Ma, W.,Ding, T.,Zhang, F.,Wu, X.,Hu, J.,Liu, S.L.,Qin, C.,Wang, X.,Xu, Z.,Rao, Z.; Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies; Nat Microbiol, 3:287-294, 2018; PubMed: 29379207; DOI: 10.1038/s41564-017-0099-x

Experimental method

X-RAY DIFFRACTION (2.206 Å)