5YVG
Crystal structure of Karyopherin beta2 in complex with FUS(full length)
Summary for 5YVG
| Entry DOI | 10.2210/pdb5yvg/pdb |
| Descriptor | Transportin-1, RNA-binding protein FUS (2 entities in total) |
| Functional Keywords | importin family, protein transport, protein transport-rna binding protein complex, protein transport/rna binding protein |
| Biological source | Homo sapiens (Human) More |
| Cellular location | Cytoplasm: Q92973 Nucleus : P35637 |
| Total number of polymer chains | 4 |
| Total formula weight | 303898.28 |
| Authors | Yoshizawa, T.,Fung, H.Y.J.,Chook, Y.M. (deposition date: 2017-11-25, release date: 2018-05-16, Last modification date: 2023-11-22) |
| Primary citation | Yoshizawa, T.,Ali, R.,Jiou, J.,Fung, H.Y.J.,Burke, K.A.,Kim, S.J.,Lin, Y.,Peeples, W.B.,Saltzberg, D.,Soniat, M.,Baumhardt, J.M.,Oldenbourg, R.,Sali, A.,Fawzi, N.L.,Rosen, M.K.,Chook, Y.M. Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173:693-705.e22, 2018 Cited by PubMed: 29677513DOI: 10.1016/j.cell.2018.03.003 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (4.05 Å) |
Structure validation
Download full validation report
