5YVE
Crystal structure of human P2X3 receptor in complex with the AF-219 negative allosteric modulator
Summary for 5YVE
Entry DOI | 10.2210/pdb5yve/pdb |
Descriptor | P2X purinoceptor 3, MAGNESIUM ION, SODIUM ION, ... (5 entities in total) |
Functional Keywords | ion channels, atp, transport protein |
Biological source | Homo sapiens (Human) |
Cellular location | Membrane; Multi-pass membrane protein: P56373 |
Total number of polymer chains | 1 |
Total formula weight | 41737.19 |
Authors | Wang, Y.,Hattori, M. (deposition date: 2017-11-25, release date: 2018-04-04, Last modification date: 2024-10-16) |
Primary citation | Wang, J.,Wang, Y.,Cui, W.W.,Huang, Y.,Yang, Y.,Liu, Y.,Zhao, W.S.,Cheng, X.Y.,Sun, W.S.,Cao, P.,Zhu, M.X.,Wang, R.,Hattori, M.,Yu, Y. Druggable negative allosteric site of P2X3 receptors. Proc. Natl. Acad. Sci. U.S.A., 115:4939-4944, 2018 Cited by PubMed: 29674445DOI: 10.1073/pnas.1800907115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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