5YUP
Crystal Structure of the Fab fragment of FVIIa antibody mAb4F5
Summary for 5YUP
Entry DOI | 10.2210/pdb5yup/pdb |
Descriptor | the heavy chain of the Fab fragment of FVIIa antibody mAb4F5, the light chain of the Fab fragment of FVIIa antibody mAb4F5 (3 entities in total) |
Functional Keywords | fviia, antibodies, fab4f5, inhibition, coagulation, structural protein, immune system |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 47423.72 |
Authors | Jiang, L.G.,Persson, E.,Huang, M.D. (deposition date: 2017-11-22, release date: 2019-06-19, Last modification date: 2023-11-22) |
Primary citation | Jiang, L.G.,Xie, X.,Li, J.,Persson, E.,Huang, M.D. Crystal structure, epitope, and functional impact of an antibody against a superactive FVIIa provide insights into allosteric mechanism. Res Pract Thromb Haemost, 3:412-419, 2019 Cited by PubMed: 31294329DOI: 10.1002/rth2.12211 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
Download full validation report