5YUP

Crystal Structure of the Fab fragment of FVIIa antibody mAb4F5

5YUP の概要

• エントリーDOI: 10.2210/pdb5yup/pdb
• 分子名称: the heavy chain of the Fab fragment of FVIIa antibody mAb4F5, the light chain of the Fab fragment of FVIIa antibody mAb4F5 (3 entities in total)
• 機能のキーワード: fviia, antibodies, fab4f5, inhibition, coagulation, structural protein, immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47423.72

構造登録者

Jiang, L.G.,Persson, E.,Huang, M.D. (登録日: 2017-11-22, 公開日: 2019-06-19, 最終更新日: 2023-11-22)

• 主引用文献: Jiang, L.G.,Xie, X.,Li, J.,Persson, E.,Huang, M.D.; Crystal structure, epitope, and functional impact of an antibody against a superactive FVIIa provide insights into allosteric mechanism.; Res Pract Thromb Haemost, 3:412-419, 2019; PubMed: 31294329; DOI: 10.1002/rth2.12211

実験手法

X-RAY DIFFRACTION (1.81 Å)