5YUF
Crystal Structure of PML RING tetramer
Summary for 5YUF
Entry DOI | 10.2210/pdb5yuf/pdb |
Descriptor | Protein PML, ZINC ION (3 entities in total) |
Functional Keywords | pml nuclear body biogenesis, sumoylation, ring tetramerization, pml-rara, targeted therapy, oncoprotein |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus: P29590 |
Total number of polymer chains | 4 |
Total formula weight | 22985.64 |
Authors | Wang, P.,Benhend, S.,Wu, H.,Breitenbach, V.,Zhen, T.,Jollivet, F.,Peres, L.,Li, Y.,Chen, S.,Chen, Z.,de THE, H.,Meng, G. (deposition date: 2017-11-22, release date: 2018-04-11) |
Primary citation | Wang, P.,Benhenda, S.,Wu, H.,Lallemand-Breitenbach, V.,Zhen, T.,Jollivet, F.,Peres, L.,Li, Y.,Chen, S.J.,Chen, Z.,de The, H.,Meng, G. RING tetramerization is required for nuclear body biogenesis and PML sumoylation. Nat Commun, 9:1277-1277, 2018 Cited by PubMed: 29599493DOI: 10.1038/s41467-018-03498-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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