5YTF

Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base M-fC pair with dA

5YTF の概要

• エントリーDOI: 10.2210/pdb5ytf/pdb
• 分子名称: DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(92F)P*GP*GP*TP*C)-3'), ... (7 entities in total)
• 機能のキーワード: dna polymerase, host-guest complex, transferase-dna complex, transferase/dna
• 由来する生物種: Thermus aquaticus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 70140.68

構造登録者

Zeng, H.,Mondal, M.,Song, R.Y.,Zhang, J.,Xia, B.,Gao, Y.Q.,Yi, C.Q. (登録日: 2017-11-17, 公開日: 2018-11-21, 最終更新日: 2023-11-22)

• 主引用文献: Zeng, H.,Mondal, M.,Song, R.,Zhang, J.,Xia, B.,Liu, M.,Zhu, C.,He, B.,Gao, Y.Q.,Yi, C.; Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry.; Angew. Chem. Int. Ed. Engl., 58:130-133, 2019; PubMed: 30407705; DOI: 10.1002/anie.201807845

実験手法

X-RAY DIFFRACTION (1.98 Å)