5YNJ

Crystal structure of MERS-CoV nsp16/nsp10 complex bound to m7GpppG

Summary for 5YNJ

Descriptornsp16 protein, nsp10 protein, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, ... (5 entities in total)
Functional Keywordsinhibitor, complex, transferase
Biological sourceHuman betacoronavirus 2c EMC/2012
Total number of polymer chains2
Total molecular weight49574.75
Authors
Wei, S.M.,Yang, L.,Ke, Z.H.,Chen, Y.,Guo, D.Y.,Fan, C.P. (deposition date: 2017-10-24, release date: 2018-12-05)
Primary citation
Wei, S.M.,Yang, L.,Ke, Z.H.,Liu, Q.Y.,Yang, Z.Z.,Chen, Y.,Guo, D.Y.,Fa, C.P.
Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.043 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21720 0.3% 5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution