Crystal structure of MERS-CoV nsp16/nsp10 complex bound to m7GpppA

Summary for 5YNF

Descriptornsp16 protein, nsp10 protein, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywordsinhibitor, complex, transferase
Biological sourceHuman betacoronavirus 2c EMC/2012
Total number of polymer chains2
Total molecular weight49558.75
Wei, S.M.,Yang, L.,Ke, Z.H.,Chen, Y.,Guo, D.Y. (deposition date: 2017-10-24, release date: 2018-12-05)
Primary citation
Wei, S.M.,Yang, L.,Ke, Z.H.,Yang, Z.Z.,Liu, Q.Y.,Chen, Y.,Guo, D.Y.,Fan, C.P.
Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2012 0.2% 0.3% 7.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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