5YKP
Human methionine aminopeptidase type 1b (F309M mutant) in complex with ovalicin
Summary for 5YKP
Entry DOI | 10.2210/pdb5ykp/pdb |
Descriptor | Methionine aminopeptidase 1, COBALT (II) ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | selective inhibition, streptococcal pneumoniae, enterococcus feacalis, metal binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 34774.31 |
Authors | Arya, T.,Pillalamarri, V.,Addlagatta, A. (deposition date: 2017-10-15, release date: 2018-10-17, Last modification date: 2023-11-22) |
Primary citation | Pillalamarri, V.,Arya, T.,Haque, N.,Bala, S.C.,Marapaka, A.K.,Addlagatta, A. Discovery of natural product ovalicin sensitive type 1 methionine aminopeptidases: molecular and structural basis. Biochem. J., 476:991-1003, 2019 Cited by PubMed: 30837307DOI: 10.1042/BCJ20180874 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
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