5YK2

The complex structure of Rv3197-erythromycin from Mycobacterium tuberculosis

5YK2 の概要

• エントリーDOI: 10.2210/pdb5yk2/pdb
• 分子名称: Probable conserved ATP-binding protein ABC transporter, ERYTHROMYCIN A (2 entities in total)
• 機能のキーワード: mycobacterium tuberculosis, macrolide antibiotic binding protein, non-canonical abc protein, transport protein
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 50333.21

構造登録者

Rao, Z.H.,Zhang, Q.Q. (登録日: 2017-10-11, 公開日: 2018-02-07, 最終更新日: 2023-11-22)

• 主引用文献: Zhang, Q.,Liu, H.,Liu, X.,Jiang, D.,Zhang, B.,Tian, H.,Yang, C.,Guddat, L.W.,Yang, H.,Mi, K.,Rao, Z.; Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target.; Protein Cell, 9:971-975, 2018; PubMed: 29350349; DOI: 10.1007/s13238-017-0502-7

実験手法

X-RAY DIFFRACTION (2.807 Å)