5YHT

Crystal structure of a phosphatase from Mycobacterium tuberculosis in complex with its substrate

Summary for 5YHT

• Entry DOI: 10.2210/pdb5yht/pdb
• Related: 5YFL
• Descriptor: Histidinol-phosphatase, ZINC ION, PHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ESTER, ... (6 entities in total)
• Functional Keywords: mycobacterium tuberculosis, phosphatase, histidinol, enzyme activity, hydrolase
• Biological source: Mycobacterium tuberculosis H37Rv
• Total number of polymer chains: 2
• Total formula weight: 58214.20

Authors

Biswal, B.K.,Jha, B. (deposition date: 2017-09-29, release date: 2018-05-23, Last modification date: 2023-11-22)

• Primary citation: Jha, B.,Kumar, D.,Sharma, A.,Dwivedy, A.,Singh, R.,Biswal, B.K.; Identification and structural characterization of a histidinol phosphate phosphatase fromMycobacterium tuberculosis; J. Biol. Chem., 293:10102-10118, 2018; PubMed: 29752410; DOI: 10.1074/jbc.RA118.002299

Experimental method

X-RAY DIFFRACTION (2.87 Å)