5YGV

Crystal structure of the abscisic acid receptor PYR1 in complex with an antagonist

Summary for 5YGV

Entry DOI	10.2210/pdb5ygv/pdb
Descriptor	Abscisic acid receptor PYR1, (2Z,4E)-3-methyl-5-[(1S,4S)-2,6,6-trimethyl-4-[3-(4-methylphenyl)prop-2-ynoxy]-1-oxidanyl-cyclohex-2-en-1-yl]penta-2,4-dienoic acid (3 entities in total)
Functional Keywords	hormone receptor
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Cellular location	Cytoplasm : O49686
Total number of polymer chains	2
Total formula weight	51653.98
Authors	Akiyama, T.,Sue, M.,Takeuchi, J.,Mimura, N.,Okamoto, M.,Monda, K.,Iba, K.,Ohnishi, T.,Todoroki, Y.,Yajima, S. (deposition date: 2017-09-27, release date: 2018-04-18, Last modification date: 2023-11-22)
Primary citation	Takeuchi, J.,Mimura, N.,Okamoto, M.,Yajima, S.,Sue, M.,Akiyama, T.,Monda, K.,Iba, K.,Ohnishi, T.,Todoroki, Y. Structure-Based Chemical Design of Abscisic Acid Antagonists That Block PYL-PP2C Receptor Interactions. ACS Chem. Biol., 13:1313-1321, 2018 Cited by PubMed: 29620349 DOI: 10.1021/acschembio.8b00105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation