5YDL

The crystal structure of the Acyl Transferase domain of SpnD complex with 2-(pent-4-yn-1-yl)malonyl

Summary for 5YDL

• Entry DOI: 10.2210/pdb5ydl/pdb
• Descriptor: PKS, (2R)-2-methanoylhept-6-ynoic acid (3 entities in total)
• Functional Keywords: pks, acyl transferase domain, transferase
• Biological source: Streptomyces sp. CNQ431
• Total number of polymer chains: 1
• Total formula weight: 46402.61

Authors

Li, Y.,Qu, X.D.,Zhou, J.H. (deposition date: 2017-09-13, release date: 2018-05-23)

• Primary citation: Li, Y.,Zhang, W.,Zhang, H.,Tian, W.Y.,Wu, L.,Wang, S.W.,Zheng, M.M.,Zhang, J.R.,Sun, C.H.,Deng, Z.X.,Sun, Y.H.,Qu, X.D.,Zhou, J.H.; Structural Basis of a Broadly Selective Acyltransferase from the Polyketide Synthase of Splenocin.; Angew. Chem. Int. Ed. Engl., 57:5823-5827, 2018; PubMed: 29536601; DOI: 10.1002/anie.201802805

Experimental method

X-RAY DIFFRACTION (2.402 Å)