5YD6

Crystal structure of PG-bound Nurr1-LBD

Summary for 5YD6

• Entry DOI: 10.2210/pdb5yd6/pdb
• Related: 5Y41
• Descriptor: Nuclear receptor subfamily 4 group A member 2, (~{Z})-7-[(1~{R},5~{S})-2-oxidanylidene-5-[(~{E},3~{S})-3-oxidanyloct-1-enyl]cyclopent-3-en-1-yl]hept-5-enoic acid, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: nurr1, lbd, prostaglandin, transcription, michael addition
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 123691.43

Authors

Sreekanth, R.,Yoon, H.S. (deposition date: 2017-09-11, release date: 2019-03-27, Last modification date: 2024-11-20)

• Primary citation: Rajan, S.,Toh, H.T.,Lim, K.H.,Yoon, H.S.; Structure of Nurr1 bound to cyclopentenone prostaglandin A2 and its mechanism of action in ameliorating dopaminergic neurodegeneration in Drosophila; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.34 Å)