Crystal structure of HPV59 pentamer in complex with the Fab fragment of antibody 28F10

Summary for 5Y9F

DescriptorMajor capsid protein L1, light chains of Fab fragment of antibody 28F10, heavy chain of Fab fragment of antibody 28F10 (3 entities in total)
Functional Keywordscapsid protein, immune complex, structural protein, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman papillomavirus type 59
Cellular locationHost nucleus  Q81971
Total number of polymer chains30
Total molecular weight1040009.02
Li, S.W.,Li, Z.H. (deposition date: 2017-08-24, release date: 2017-10-25)
Primary citation
Li, Z.,Wang, D.,Gu, Y.,Song, S.,He, M.,Shi, J.,Liu, X.,Wei, S.,Li, J.,Yu, H.,Zheng, Q.,Yan, X.,Baker, T.S.,Zhang, J.,McLellan, J.S.,Li, S.,Xia, N.
Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus.
MBio, 8:-, 2017
PubMed: 28951471 (PDB entries with the same primary citation)
DOI: 10.1128/mBio.00787-17
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26180.6%3.0%10.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution