5Y9A

Crystal structure of the complex of peptidyl tRNA hydrolase with a phosphate ion at the substrate binding site and cytarabine at a new ligand binding site at 1.1 A resolution

Replaces:  4LWR

Summary for 5Y9A

• Entry DOI: 10.2210/pdb5y9a/pdb
• Descriptor: Peptidyl-tRNA hydrolase, CYTARABINE, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: hydrolase
• Biological source: Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / CIP 70.34 / JCM 6841 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81)
• Total number of polymer chains: 1
• Total formula weight: 21588.42

Authors

Kaushik, S.,Iqbal, N.,Singh, N.,Singh, P.K.,Sharma, S.,Singh, T.P. (deposition date: 2017-08-23, release date: 2017-09-13, Last modification date: 2023-11-22)

• Primary citation: Kaushik, S.,Iqbal, N.,Singh, N.,Sikarwar, J.S.,Singh, P.K.,Sharma, P.,Kaur, P.,Sharma, S.,Owais, M.,Singh, T.P.; Search of multiple hot spots on the surface of peptidyl-tRNA hydrolase: structural, binding and antibacterial studies.; Biochem. J., 475:547-560, 2018; PubMed: 29301982; DOI: 10.1042/BCJ20170666

Experimental method

X-RAY DIFFRACTION (1.1 Å)