5Y7K
Crystal structure of human DPP4 in complex with inhibitor1
Summary for 5Y7K
Entry DOI | 10.2210/pdb5y7k/pdb |
Descriptor | Dipeptidyl peptidase 4, (R)-4-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazine-2-one (3 entities in total) |
Functional Keywords | dpp4, inhibitor, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 339456.16 |
Authors | |
Primary citation | Lee, H.K.,Kim, M.K.,Kim, H.D.,Kim, H.J.,Kim, J.W.,Lee, J.O.,Kim, C.W.,Kim, E.E. Unique binding mode of Evogliptin with human dipeptidyl peptidase IV. Biochem.Biophys.Res.Commun., 494:452-459, 2017 Cited by PubMed: 29061303DOI: 10.1016/j.bbrc.2017.10.101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.512 Å) |
Structure validation
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