5Y3Q
Crystal structure of SARS coronavirus papain-like protease conjugated with beta-mercaptoethanol
5Y3Q の概要
エントリーDOI | 10.2210/pdb5y3q/pdb |
分子名称 | Replicase polyprotein 1a, ZINC ION, BETA-MERCAPTOETHANOL, ... (6 entities in total) |
機能のキーワード | complex structure, hydrolase |
由来する生物種 | Human SARS coronavirus (SARS-CoV) |
細胞内の位置 | Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region : P0C6U8 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 36904.91 |
構造登録者 | |
主引用文献 | Lin, M.H.,Moses, D.C.,Hsieh, C.H.,Cheng, S.C.,Chen, Y.H.,Sun, C.Y.,Chou, C.Y. Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes Antiviral Res., 150:155-163, 2017 Cited by PubMed: 29289665DOI: 10.1016/j.antiviral.2017.12.015 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.65 Å) |
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