5Y1B
Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with a berberine derivative (SYSU-00679)
Summary for 5Y1B
Entry DOI | 10.2210/pdb5y1b/pdb |
Descriptor | Beta-hexosaminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-3'-quinolinium propylberberine, ... (4 entities in total) |
Functional Keywords | ostrinia furnacalis, beta-n-acetyl-d-hexosaminidase inhibitor, berberine derivative, hydrolase |
Biological source | Ostrinia furnacalis (Asian corn borer) |
Total number of polymer chains | 1 |
Total formula weight | 67315.78 |
Authors | Duan, Y.W.,Liu, T.,Zhou, Y.,Tang, J.Y.,Li, M.,Yang, Q. (deposition date: 2017-07-20, release date: 2018-01-24, Last modification date: 2023-11-22) |
Primary citation | Duan, Y.,Liu, T.,Zhou, Y.,Dou, T.,Yang, Q. Glycoside hydrolase family 18 and 20 enzymes are novel targets of the traditional medicine berberine. J. Biol. Chem., 293:15429-15438, 2018 Cited by PubMed: 30135205DOI: 10.1074/jbc.RA118.004351 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.207 Å) |
Structure validation
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