5XW6

Crystal structure of the chicken ATP-gated P2X7 receptor channel in the presence of competitive antagonist TNP-ATP at 3.1 Angstroms

5XW6 の概要

• エントリーDOI: 10.2210/pdb5xw6/pdb
• 分子名称: P2X purinoceptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE (3 entities in total)
• 機能のキーワード: ion channel, ligand-gated ion channel, p2x receptor, p2x7 receptor, tnp-atp, membrane protein
• 由来する生物種: Gallus gallus (Chicken)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 114843.98

構造登録者

Kasuya, G.,Hattori, M.,Nureki, O. (登録日: 2017-06-29, 公開日: 2017-10-25, 最終更新日: 2023-11-22)

• 主引用文献: Kasuya, G.,Yamaura, T.,Ma, X.B.,Nakamura, R.,Takemoto, M.,Nagumo, H.,Tanaka, E.,Dohmae, N.,Nakane, T.,Yu, Y.,Ishitani, R.,Matsuzaki, O.,Hattori, M.,Nureki, O.; Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel; Nat Commun, 8:876-876, 2017; PubMed: 29026074; DOI: 10.1038/s41467-017-00887-9

実験手法

X-RAY DIFFRACTION (3.1 Å)