5XO2

Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide II

5XO2 の概要

• エントリーDOI: 10.2210/pdb5xo2/pdb
• 分子名称: Paired immunoglobulin-like type 2 receptor alpha, Peptide from Envelope glycoprotein B, N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2,4-dideoxy-alpha-D-xylo-hexopyranose, ... (4 entities in total)
• 機能のキーワード: membrane protein, immune receptor, viral entry inhibitor, glycopeptide, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Cell membrane ; Single-pass type I membrane protein . Isoform 3: Secreted . Isoform 4: Secreted : Q9UKJ1; Virion membrane ; Single-pass type I membrane protein : P06437
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 30147.66

構造登録者

Furukawa, A.,Kakita, K.,Yamada, T.,Ishizuka, M.,Sakamoto, J.,Hatori, N.,Maeda, N.,Ohsaka, F.,Saitoh, T.,Nomura, T.,Kuroki, K.,Nambu, H.,Arase, H.,Matsunaga, S.,Anada, M.,Ose, T.,Hashimoto, S.,Maenaka, K. (登録日: 2017-05-25, 公開日: 2017-10-25, 最終更新日: 2023-11-22)

• 主引用文献: Furukawa, A.,Kakita, K.,Yamada, T.,Ishizuka, M.,Sakamoto, J.,Hatori, N.,Maeda, N.,Ohsaka, F.,Saitoh, T.,Nomura, T.,Kuroki, K.,Nambu, H.,Arase, H.,Matsunaga, S.,Anada, M.,Ose, T.,Hashimoto, S.,Maenaka, K.; Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR alpha immune cell receptor.; J. Biol. Chem., 292:21128-21136, 2017; PubMed: 29046357; DOI: 10.1074/jbc.M117.799239

実験手法

X-RAY DIFFRACTION (2.201 Å)