5XNV
Crystal structure of YEATS2 YEATS bound to H3K27ac peptide
Summary for 5XNV
Entry DOI | 10.2210/pdb5xnv/pdb |
Descriptor | YEATS domain-containing protein 2, ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, ... (5 entities in total) |
Functional Keywords | epigenetics, histone reader, histone acetylation, protein complex, protein binding-peptide complex, protein binding/peptide |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9ULM3 |
Total number of polymer chains | 2 |
Total formula weight | 16721.60 |
Authors | Li, H.T.,Guan, H.P.,Zhao, D. (deposition date: 2017-05-24, release date: 2017-11-01, Last modification date: 2023-11-22) |
Primary citation | Mi, W.,Guan, H.,Lyu, J.,Zhao, D.,Xi, Y.,Jiang, S.,Andrews, F.H.,Wang, X.,Gagea, M.,Wen, H.,Tora, L.,Dent, S.Y.R.,Kutateladze, T.G.,Li, W.,Li, H.,Shi, X. YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer. Nat Commun, 8:1088-1088, 2017 Cited by PubMed: 29057918DOI: 10.1038/s41467-017-01173-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.696 Å) |
Structure validation
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