5XMB

Mycobacterium tuberculosis Pantothenate kinase mutant F247A

5XMB の概要

• エントリーDOI: 10.2210/pdb5xmb/pdb
• 分子名称: Pantothenate kinase, SULFATE ION (3 entities in total)
• 機能のキーワード: homodimer, coa biosynthesis, nucleotide binding, concerted movement, structural transformation, transferase
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 142899.27

構造登録者

Paul, A.,Kumar, P.,Surolia, A.,Vijayan, M. (登録日: 2017-05-13, 公開日: 2018-05-16, 最終更新日: 2023-11-22)

• 主引用文献: Paul, A.,Kumar, P.,Surolia, A.,Vijayan, M.; Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase; Acta Crystallogr F Struct Biol Commun, 73:635-643, 2017; PubMed: 29095158; DOI: 10.1107/S2053230X17015667

実験手法

X-RAY DIFFRACTION (3.2 Å)