5XI5
Crystal structure of T2R-TTL-PO5 complex
Summary for 5XI5
Entry DOI | 10.2210/pdb5xi5/pdb |
Descriptor | Tubulin alpha chain, (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total) |
Functional Keywords | tubulin, microtubule, colchicine, stathmin, structural protein |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cytoplasm, cytoskeleton : A0A0R4I993 A0A0R4I995 Golgi apparatus : P63043 |
Total number of polymer chains | 6 |
Total formula weight | 269897.16 |
Authors | |
Primary citation | Chu, Y.,Wang, Y.,Yang, J.,Li, W. Synthesis, biological evaluation and X-ray structure of anti-microtubule agents To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
Download full validation report