5XG4
Crystal structure of uPA in complex with quercetin
Summary for 5XG4
Entry DOI | 10.2210/pdb5xg4/pdb |
Descriptor | Urokinase-type plasminogen activator, 3,5,7,3',4'-PENTAHYDROXYFLAVONE, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, ... (4 entities in total) |
Functional Keywords | serine proteases, upa, pepetide inhibitors, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P00749 |
Total number of polymer chains | 1 |
Total formula weight | 28284.17 |
Authors | |
Primary citation | Xue, G.,Gong, L.,Yuan, C.,Xu, M.,Wang, X.,Jiang, L.,Huang, M. A structural mechanism of flavonoids in inhibiting serine proteases Food Funct, 8:2437-2443, 2017 Cited by PubMed: 28644504DOI: 10.1039/c6fo01825d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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