5XFW

Crystal structures of FMN-free form of dihydroorotate dehydrogenase from Trypanosoma brucei

Summary for 5XFW

• Entry DOI: 10.2210/pdb5xfw/pdb
• Related: 5XFV
• Descriptor: Dihydroorotate dehydrogenase (fumarate), MALONATE ION (3 entities in total)
• Functional Keywords: neglected tropical diseases flavin enzyme pyrimidine metabolism, oxidoreductase
• Biological source: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
• Cellular location: Cytoplasm : Q57U83
• Total number of polymer chains: 4
• Total formula weight: 147386.28

Authors

Kubota, T.,Tani, O.,Yamaguchi, T.,Namatame, I.,Sakashita, H.,Furukawa, K.,Yamasaki, K. (deposition date: 2017-04-11, release date: 2018-04-25, Last modification date: 2023-11-22)

• Primary citation: Kubota, T.,Tani, O.,Yamaguchi, T.,Namatame, I.,Sakashita, H.,Furukawa, K.,Yamasaki, K.; Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase fromTrypanosoma brucei.; FEBS Open Bio, 8:680-691, 2018; PubMed: 29632820; DOI: 10.1002/2211-5463.12403

Experimental method

X-RAY DIFFRACTION (1.6 Å)