Summary for 5XEW
Entry DOI | 10.2210/pdb5xew/pdb |
Related | 5ERZ 5ES0 |
Descriptor | DNA (5'-D(*TP*TP*CP*CP*GP*CP*CP*GP*CP*CP*GP*AP*A)-3'), 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, ... (6 entities in total) |
Functional Keywords | trinucleotide repeats, neurological disease, induced fit recognition, metal binding ligand, consecutive bases flip-out, dna deformation, molecular diagnostics, dna-antibiotic complex, dna/antibiotic |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 10343.74 |
Authors | Tseng, W.H.,Wu, P.C.,Hou, M.H. (deposition date: 2017-04-06, release date: 2017-06-21, Last modification date: 2024-03-27) |
Primary citation | Tseng, W.H.,Chang, C.K.,Wu, P.C.,Hu, N.J.,Lee, G.H.,Tzeng, C.C.,Neidle, S.,Hou, M.H. Induced-Fit Recognition of CCG Trinucleotide Repeats by a Nickel-Chromomycin Complex Resulting in Large-Scale DNA Deformation Angew. Chem. Int. Ed. Engl., 56:8761-8765, 2017 Cited by PubMed: 28544401DOI: 10.1002/anie.201703989 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.751 Å) |
Structure validation
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