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5XEJ

Crystal Structure of Macrophage Migration Inhibitory Factor bound to MTX

Replaces:  5CG4
Summary for 5XEJ
Entry DOI10.2210/pdb5xej/pdb
DescriptorMacrophage migration inhibitory factor, SULFATE ION, (2~{R})-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid, ... (4 entities in total)
Functional Keywordsisomerase-inhibitor complex, isomerase/inhibitor
Biological sourceHomo sapiens (Human)
Total number of polymer chains3
Total formula weight37903.86
Authors
Takimoto-Kamimura, M.,Fukushima, K. (deposition date: 2017-04-05, release date: 2018-07-25, Last modification date: 2023-11-22)
Primary citationFukushima, K.,Furuya, M.,Kamimura, T.,Takimoto-Kamimura, M.
Structure of macrophage migration inhibitory factor in complex with methotrexate.
Acta Crystallogr D Struct Biol, 77:293-299, 2021
Cited by
PubMed: 33645533
DOI: 10.1107/S2059798321000474
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

222036

건을2024-07-03부터공개중

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