5XE8

Crystal Structure of the Peptidase Domain of Streptococcus mutans ComA

Summary for 5XE8

Entry DOI	10.2210/pdb5xe8/pdb
Related	5XE9
Descriptor	Putative ABC transporter, ATP-binding protein ComA, DI(HYDROXYETHYL)ETHER (3 entities in total)
Functional Keywords	peptidase, quorum-sensing, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Streptococcus mutans serotype c
Total number of polymer chains	2
Total formula weight	34919.89
Authors	Ishii, S.,Fukui, K.,Yokoshima, S.,Kumagai, K.,Beniyama, Y.,Kodama, T.,Fukuyama, T.,Okabe, T.,Nagano, T.,Kojima, H.,Yano, T. (deposition date: 2017-04-03, release date: 2017-06-28, Last modification date: 2023-11-22)
Primary citation	Ishii, S.,Fukui, K.,Yokoshima, S.,Kumagai, K.,Beniyama, Y.,Kodama, T.,Fukuyama, T.,Okabe, T.,Nagano, T.,Kojima, H.,Yano, T. High-throughput Screening of Small Molecule Inhibitors of the Streptococcus Quorum-sensing Signal Pathway Sci Rep, 7:4029-4029, 2017 Cited by PubMed: 28642545 DOI: 10.1038/s41598-017-03567-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation