Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5X9O

Crystal structure of the BCL6 BTB domain in complex with Compound 1a

Summary for 5X9O
Entry DOI10.2210/pdb5x9o/pdb
Related5X9P
DescriptorB-cell lymphoma 6 protein, 5-[(2-chloranyl-4-nitro-phenyl)amino]-1,3-dihydrobenzimidazol-2-one, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywordstranscription repressor, transcription-inhibitor complex, transcription/inhibitor
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : P41182
Total number of polymer chains1
Total formula weight16693.59
Authors
Sogabe, S.,Ida, K.,Lane, W.,Snell, G. (deposition date: 2017-03-08, release date: 2017-08-16, Last modification date: 2023-11-22)
Primary citationYasui, T.,Yamamoto, T.,Sakai, N.,Asano, K.,Takai, T.,Yoshitomi, Y.,Davis, M.,Takagi, T.,Sakamoto, K.,Sogabe, S.,Kamada, Y.,Lane, W.,Snell, G.,Iwata, M.,Goto, M.,Inooka, H.,Sakamoto, J.I.,Nakada, Y.,Imaeda, Y.
Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug design
Bioorg. Med. Chem., 25:4876-4886, 2017
Cited by
PubMed: 28760529
DOI: 10.1016/j.bmc.2017.07.037
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.58 Å)
Structure validation

217705

건을2024-03-27부터공개중

PDB statisticsPDBj update infoContact PDBjnumon