5X8G
Binary complex structure of a double mutant I454RA456K of o-Succinylbenzoate CoA Synthetase (MenE) from Bacillus Subtilis bound with its product analogue OSB-NCoA at 1.90 angstrom
5X8G の概要
エントリーDOI | 10.2210/pdb5x8g/pdb |
分子名称 | 2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-N-coenzyme A, MAGNESIUM ION, ... (7 entities in total) |
機能のキーワード | adenylate-forming enzyme, acyl-coa synthetase, thioester conformation, coa, pantetheine tunnel, adp binding subsite, domain alternation, large conformational change, inter-domain linker, ligase |
由来する生物種 | Bacillus subtilis subsp. subtilis str. 168 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 222107.59 |
構造登録者 | |
主引用文献 | Chen, Y.,Li, T.L.,Lin, X.,Li, X.,Li, X.D.,Guo, Z. Crystal structure of the thioesterification conformation of Bacillus subtilis o-succinylbenzoyl-CoA synthetase reveals a distinct substrate-binding mode J. Biol. Chem., 292:12296-12310, 2017 Cited by PubMed: 28559280DOI: 10.1074/jbc.M117.790410 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.9 Å) |
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