5X8F
Ternary complex structure of a double mutant I454RA456K of o-Succinylbenzoate CoA Synthetase (MenE) from Bacillus Subtilis bound with AMP and its product analogue OSB-NCoA at 1.76 angstrom
Summary for 5X8F
Entry DOI | 10.2210/pdb5x8f/pdb |
Related | 5X8G |
Descriptor | 2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-N-coenzyme A, ADENOSINE MONOPHOSPHATE, ... (8 entities in total) |
Functional Keywords | adenylate-forming enzyme, acyl-coa synthetase, thioester conformation, coa, pantetheine tunnel, adp binding subsite, domain alternation, large conformational change, inter-domain linker, ligase |
Biological source | Bacillus subtilis subsp. subtilis str. 168 |
Total number of polymer chains | 4 |
Total formula weight | 223682.85 |
Authors | |
Primary citation | Chen, Y.,Li, T.L.,Lin, X.,Li, X.,Li, X.D.,Guo, Z. Crystal structure of the thioesterification conformation of Bacillus subtilis o-succinylbenzoyl-CoA synthetase reveals a distinct substrate-binding mode J. Biol. Chem., 292:12296-12310, 2017 Cited by PubMed: 28559280DOI: 10.1074/jbc.M117.790410 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.763 Å) |
Structure validation
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