5X6M

Crystal Structure of SMAD5-MH1 in complex with a composite DNA sequence

Replaces:  4ZL3

Summary for 5X6M

• Entry DOI: 10.2210/pdb5x6m/pdb
• Related: 5X6G 5X6H
• Descriptor: Mothers against decapentaplegic homolog 5, DNA (5'-D(P*AP*TP*CP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*AP*TP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*GP*A)-3'), ... (4 entities in total)
• Functional Keywords: smad5 mh1 domain, composite dna, sbe dna, gc-rich dna, metal binding protein-dna complex, metal binding protein/dna
• Biological source: Mus musculus (Mouse); More
• Cellular location: Cytoplasm : P97454
• Total number of polymer chains: 8
• Total formula weight: 96558.05

Authors

Chai, N.,Wang, J.,Wang, Z.X.,Wu, J.W. (deposition date: 2017-02-22, release date: 2017-03-15, Last modification date: 2023-11-22)

• Primary citation: Chai, N.,Li, W.X.,Wang, J.,Wang, Z.X.,Yang, S.M.,Wu, J.W.; Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.; Nucleic Acids Res., 43:9051-9064, 2015; PubMed: 26304548; DOI: 10.1093/nar/gkv848

Experimental method

X-RAY DIFFRACTION (3.2 Å)