5WWX

Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA

Summary for 5WWX

• Entry DOI: 10.2210/pdb5wwx/pdb
• Related: 5WWW 5WWZ
• Descriptor: RNA-binding E3 ubiquitin-protein ligase MEX3C, RNA (5'-R(P*AP*GP*AP*GP*U)-3'), NICKEL (II) ION, ... (4 entities in total)
• Functional Keywords: kh2, mex-3c, rna, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm : Q5U5Q3
• Total number of polymer chains: 2
• Total formula weight: 11440.95

Authors

Yang, L.,Wang, C.,Li, F.,Gong, Q. (deposition date: 2017-01-05, release date: 2017-08-23, Last modification date: 2023-11-22)

• Primary citation: Yang, L.,Wang, C.,Li, F.,Zhang, J.,Nayab, A.,Wu, J.,Shi, Y.,Gong, Q.; The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity; J. Biol. Chem., 292:16221-16234, 2017; PubMed: 28808060; DOI: 10.1074/jbc.M117.797746

Experimental method

X-RAY DIFFRACTION (2 Å)