5WWP

Crystal structure of Middle East respiratory syndrome coronavirus helicase (MERS-CoV nsp13)

Summary for 5WWP

Entry DOI	10.2210/pdb5wwp/pdb
Descriptor	ORF1ab, ZINC ION, SULFATE ION (3 entities in total)
Functional Keywords	middle east respiratory syndrome coronavirus, nidovirales, coronavirus, mers, nsp13, helicase, sf1 superfamily, atp hydrolysis, atpase, rna 5'-triphosphatase, unwinding, upf1 helicase, arterivirus nsp10, zinc binding domain, ch domain, 1b beta-barrel domain, viral rna synthesis, reca-like domain, cov replication and transcription, hydrolase
Biological source	Human betacoronavirus 2c EMC/2012
Cellular location	Host cytoplasm, host perinuclear region . Host membrane ; Multi-pass membrane protein : K0BWD0
Total number of polymer chains	2
Total formula weight	133548.54
Authors	Hao, W.,Wojdyla, J.A.,Zhao, R.,Han, R.,Das, R.,Zlatev, I.,Manoharan, M.,Wang, M.,Cui, S. (deposition date: 2017-01-03, release date: 2017-07-05, Last modification date: 2021-09-15)
Primary citation	Hao, W.,Wojdyla, J.A.,Zhao, R.,Han, R.,Das, R.,Zlatev, I.,Manoharan, M.,Wang, M.,Cui, S. Crystal structure of Middle East respiratory syndrome coronavirus helicase PLoS Pathog., 13:e1006474-e1006474, 2017 Cited by PubMed: 28651017 DOI: 10.1371/journal.ppat.1006474 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation