5WWP

Crystal structure of Middle East respiratory syndrome coronavirus helicase (MERS-CoV nsp13)

5WWP の概要

• エントリーDOI: 10.2210/pdb5wwp/pdb
• 分子名称: ORF1ab, ZINC ION, SULFATE ION (3 entities in total)
• 機能のキーワード: middle east respiratory syndrome coronavirus, nidovirales, coronavirus, mers, nsp13, helicase, sf1 superfamily, atp hydrolysis, atpase, rna 5'-triphosphatase, unwinding, upf1 helicase, arterivirus nsp10, zinc binding domain, ch domain, 1b beta-barrel domain, viral rna synthesis, reca-like domain, cov replication and transcription, hydrolase
• 由来する生物種: Human betacoronavirus 2c EMC/2012
• 細胞内の位置: Host cytoplasm, host perinuclear region . Host membrane ; Multi-pass membrane protein : K0BWD0
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 133548.54

構造登録者

Hao, W.,Wojdyla, J.A.,Zhao, R.,Han, R.,Das, R.,Zlatev, I.,Manoharan, M.,Wang, M.,Cui, S. (登録日: 2017-01-03, 公開日: 2017-07-05, 最終更新日: 2021-09-15)

• 主引用文献: Hao, W.,Wojdyla, J.A.,Zhao, R.,Han, R.,Das, R.,Zlatev, I.,Manoharan, M.,Wang, M.,Cui, S.; Crystal structure of Middle East respiratory syndrome coronavirus helicase; PLoS Pathog., 13:e1006474-e1006474, 2017; PubMed: 28651017; DOI: 10.1371/journal.ppat.1006474

実験手法

X-RAY DIFFRACTION (3 Å)