5WSY

The complex structure of SAV606 with N-carboxymethyl-3-aminobutyrate

Summary for 5WSY

• Entry DOI: 10.2210/pdb5wsy/pdb
• Related: 5WSX
• Descriptor: Uncharacterized protein, (3~{R})-3-(2-hydroxy-2-oxoethylamino)butanoic acid (3 entities in total)
• Functional Keywords: thioesterase, hotdog fold, hydrolase
• Biological source: Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
• Total number of polymer chains: 2
• Total formula weight: 39534.55

Authors

Chisuga, T.,Miyanaga, A.,Kudo, F.,Eguchi, T. (deposition date: 2016-12-08, release date: 2017-05-31, Last modification date: 2023-11-08)

• Primary citation: Chisuga, T.,Miyanaga, A.,Kudo, F.,Eguchi, T.; Structural analysis of the dual-function thioesterase SAV606 unravels the mechanism of Michael addition of glycine to an alpha , beta-unsaturated thioester.; J. Biol. Chem., 292:10926-10937, 2017; PubMed: 28522606; DOI: 10.1074/jbc.M117.792549

Experimental method

X-RAY DIFFRACTION (2 Å)