5WRL

Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y628 peptide

Summary for 5WRL

• Entry DOI: 10.2210/pdb5wrl/pdb
• Related: 5WRK 5WRM
• Descriptor: AP-2 complex subunit mu, Insulin receptor substrate 1 (2 entities in total)
• Functional Keywords: endocytosis, clathrin adaptor ap-2 complex subunit, peptide complex
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 2
• Total formula weight: 32767.45

Authors

Yoneyama, Y.,Niwa, H.,Umehara, T.,Yokoyama, S.,Hakuno, F.,Takahashi, S. (deposition date: 2016-12-02, release date: 2017-12-06, Last modification date: 2023-11-08)

• Primary citation: Yoneyama, Y.,Lanzerstorfer, P.,Niwa, H.,Umehara, T.,Shibano, T.,Yokoyama, S.,Chida, K.,Weghuber, J.,Hakuno, F.,Takahashi, S.I.; IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling; Elife, 7:-, 2018; PubMed: 29661273; DOI: 10.7554/eLife.32893

Experimental method

X-RAY DIFFRACTION (3.095 Å)