5WQD

Crystal structure of TRF2 TRFH in complex with an NBS1 peptide

Summary for 5WQD

• Entry DOI: 10.2210/pdb5wqd/pdb
• Descriptor: Telomeric repeat-binding factor 2, Nibrin (2 entities in total)
• Functional Keywords: telomere, shelterin complex, dna damage response, cell cycle
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q15554 O60934
• Total number of polymer chains: 14
• Total formula weight: 179206.25

Authors

Hu, C.,Chen, Y.,Lei, M. (deposition date: 2016-11-26, release date: 2017-03-08, Last modification date: 2023-11-08)

• Primary citation: Rai, R.,Hu, C.,Broton, C.,Chen, Y.,Lei, M.,Chang, S.; NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres; Mol. Cell, 65:801-817.e4, 2017; PubMed: 28216226; DOI: 10.1016/j.molcel.2017.01.016

Experimental method

X-RAY DIFFRACTION (3 Å)