5WMQ

Crystal Structure of HLA-B8 in complex with ELR, an Influenza A virus peptide

Summary for 5WMQ

Entry DOI	10.2210/pdb5wmq/pdb
Descriptor	HLA class I histocompatibility antigen, B-8 alpha chain, Beta-2-microglobulin, ELR peptide from IAV, ... (4 entities in total)
Functional Keywords	hla, viral peptide, iav, ebv, cmv, crossreactivity, tcr, t cell, heterologous immunity, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	45004.79
Authors	Gras, S.,Rossjohn, J. (deposition date: 2017-07-31, release date: 2018-06-06, Last modification date: 2020-02-26)
Primary citation	Rowntree, L.C.,Nguyen, T.H.O.,Halim, H.,Purcell, A.W.,Rossjohn, J.,Gras, S.,Kotsimbos, T.C.,Mifsud, N.A. Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses. J. Immunol., 200:3993-4003, 2018 Cited by PubMed: 29735483 DOI: 10.4049/jimmunol.1800010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation