5WIW

Crystal structure of murine 4-1BB N128A mutant from HEK293T cells in P43 space group

5WIW の概要

• エントリーDOI: 10.2210/pdb5wiw/pdb
• 分子名称: Tumor necrosis factor receptor superfamily member 9, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: tumor necrosis factor, apoptosis, immune system
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32790.06

構造登録者

Zajonc, D.M.,Bitra, A. (登録日: 2017-07-20, 公開日: 2017-12-20, 最終更新日: 2023-10-04)

• 主引用文献: Bitra, A.,Doukov, T.,Wang, J.,Picarda, G.,Benedict, C.A.,Croft, M.,Zajonc, D.M.; Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.; J. Biol. Chem., 293:1317-1329, 2018; PubMed: 29242193; DOI: 10.1074/jbc.M117.814905

実験手法

X-RAY DIFFRACTION (2.3 Å)