5WI2
Crystal structure of the KA1 domain from human Chk1
Summary for 5WI2
| Entry DOI | 10.2210/pdb5wi2/pdb |
| Descriptor | cDNA FLJ56409, highly similar to Serine/threonine-protein kinase Chk1 (EC 2.7.11.1), ACETATE ION, GLYCEROL, ... (4 entities in total) |
| Functional Keywords | kinase, checkpoint, autoinhibition, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 24336.42 |
| Authors | Emptage, R.P.,Marmorstein, R. (deposition date: 2017-07-18, release date: 2017-10-04, Last modification date: 2023-10-04) |
| Primary citation | Emptage, R.P.,Schoenberger, M.J.,Ferguson, K.M.,Marmorstein, R. Intramolecular autoinhibition of checkpoint kinase 1 is mediated by conserved basic motifs of the C-terminal kinase-associated 1 domain. J. Biol. Chem., 292:19024-19033, 2017 Cited by PubMed: 28972186DOI: 10.1074/jbc.M117.811265 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.495 Å) |
Structure validation
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