5WI2

Crystal structure of the KA1 domain from human Chk1

5WI2 の概要

• エントリーDOI: 10.2210/pdb5wi2/pdb
• 分子名称: cDNA FLJ56409, highly similar to Serine/threonine-protein kinase Chk1 (EC 2.7.11.1), ACETATE ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: kinase, checkpoint, autoinhibition, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 24336.42

構造登録者

Emptage, R.P.,Marmorstein, R. (登録日: 2017-07-18, 公開日: 2017-10-04, 最終更新日: 2023-10-04)

• 主引用文献: Emptage, R.P.,Schoenberger, M.J.,Ferguson, K.M.,Marmorstein, R.; Intramolecular autoinhibition of checkpoint kinase 1 is mediated by conserved basic motifs of the C-terminal kinase-associated 1 domain.; J. Biol. Chem., 292:19024-19033, 2017; PubMed: 28972186; DOI: 10.1074/jbc.M117.811265

実験手法

X-RAY DIFFRACTION (2.495 Å)