5WER

Crystal Structure of TAPBPR and H2-Dd complex

Summary for 5WER

• Entry DOI: 10.2210/pdb5wer/pdb
• Related: 5MES
• Descriptor: H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, TAP binding protein related, ... (7 entities in total)
• Functional Keywords: antigen presentation, peptide editing, major histompatibility complex class i, mhc-i, tapasin, peptide loading complex, plc, immune response, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 12
• Total formula weight: 346591.12

Authors

Jiang, J.S.,Natarajan, K.,Boyd, L.F.,Margulies, D.H. (deposition date: 2017-07-10, release date: 2017-10-18, Last modification date: 2019-08-28)

• Primary citation: Jiang, J.,Natarajan, K.,Boyd, L.F.,Morozov, G.I.,Mage, M.G.,Margulies, D.H.; Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.; Science, 358:1064-1068, 2017; PubMed: 29025991; DOI: 10.1126/science.aao5154

Experimental method

X-RAY DIFFRACTION (3.412 Å)