5WEQ

The crystal structure of a MR78 mutant

Summary for 5WEQ

• Entry DOI: 10.2210/pdb5weq/pdb
• Related: 5JRP
• Descriptor: MR78 mutant light chain, MR78 mutant Fab heavy chain (3 entities in total)
• Functional Keywords: marburg virus, antibody, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 47347.62

Authors

Dong, J.,Williamson, L.E.,Crowe, J.E. (deposition date: 2017-07-10, release date: 2018-04-25)

• Primary citation: Sangha, A.K.,Dong, J.,Williamson, L.,Hashiguchi, T.,Saphire, E.O.,Crowe, J.E.,Meiler, J.; Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.; Structure, 25:1820-1828.e2, 2017; PubMed: 29153506; DOI: 10.1016/j.str.2017.10.005

Experimental method

X-RAY DIFFRACTION (2 Å)